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Bone Marrow Transplantation Cost in Apollo

Bone marrow transplantation is a medical procedure that is a treatment option for various kinds of diseases and disorders of blood and bone marrow. It involves the replacement of the damaged bone marrow cells with healthy cells from the patient (self) or donor. 

This is also referred to as Haematopoietic Stem cell Transplant (HSCT) because the cells that are transplanted are called Haematopoietic stem cells, the blood-forming cells. The new healthy cells will start producing normal blood cells, resulting in improvement of the patient’s condition.

BMT-Apollo

Bone Marrow Transplant in Apollo

Apollo Hospitals, one of India’s foremost healthcare groups, is highly known for the high quality of medical care services and facilities it provides. The chain of hospitals spreads all across several major cities, includes top hospitals in India such as Indraprastha Apollo Hospital, Delhi, and Apollo Hospital Chennai, among many others. 

The bone marrow transplant at Apollo hospital is one of the best programs in the entire country. The hospital has a specialized department and units completely dedicated to BMT patients. There is a team of trained doctors and nurses specializing in the field of hematology. They are committed to providing personalized and compassionate care to all the patients. 

Bone marrow transplants in India have a very high success rate and a low complication rate, attributed to the standard of safety and clinical excellence offered by the hospitals. The medical procedure is carried out in state-of-the-art facilities with stringent pre-and post-operative protocols, limiting the risk of infections and other complications. For cancer patients, a multidisciplinary team of specialists is involved in planning the treatment and care. 

Click here to look at the Best Bone Marrow transplant hospitals in India.

The blood and marrow transplant center at Apollo Hospitals has a record of performing more than 1500 transplants with excellent clinical outcomes. Apollo Hospitals, India is a trusted name for international patients, as it receives patients from all over the world. The international patient department at the hospital guides and aids the patient and their family throughout the journey of their treatment, starting from planning the travel and during the procedure, to aftercare and follow-ups. 

To know more about Apollo Hospital Bone Marrow Transplant and receive a detailed treatment plan with cost estimates, share your medical reports with us at care@lyfboat.com. Lyfboat strives to help and guide patients to receive the best quality treatment and medical services. We provide a range of services for international patients, including airport pick up/drop off, visa assistance, arranging accommodation, language translators, and many more.  

Bone Marrow Transplant Cost in Apollo Hospital

The treatment packages offered by Indian hospitals are relatively lower than the price for the same treatment in various other countries, owing to many factors. The average bone marrow transplant cost in Apollo hospital is very affordable, starting from as low as USD 15000 (Autologous Bone Marrow Transplant for certain diseases) and range up to USD 35,000 and more, depending on the type of transplant and medical condition of the patient.

An international patient from countries such as the USA, UK, or other European countries may save 40-60% on the overall treatment cost by having their transplant surgery in India, instead of their home country. The affordability of bone marrow transplantation cost in Apollo Chennai makes it a highly favorable choice for many international patients from Bangladesh, UAE, and many other countries. 

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Overview: Bone Marrow Transplant

Bone marrow is a soft tissue found in the spongy parts of the bones. It comprises haematopoietic stem cells, marrow adipose tissue as well as some stromal cells. Bone marrow can be found in a few bones in adult humans, namely ribs, vertebrae, sternum, and hip bones (in the pelvis). Stem cells are progenitor cells with unique ability to renew and regenerate, or form undifferentiated cells that can later attain different specialized functions. 

The haematopoietic stem cells are progenitor cells for myeloid and lymphoid lineages, which means they form various types of blood cells, including red blood cells, white blood cells and platelets. 

A bone marrow transplants can a treatment option for patient suffering from certain diseases of the blood and bone marrow, including cancer and autoimmune disorders.

Stem Cell Transplant might be indicated in the following conditions:

  • Cancers of blood and marrow: Lymphoma (Hodgkin’s & Non Hodgkin’s), Myeloma, Leukemia (including Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, follicular lymphoma)
  • Genetic disorders such as Thalassemia, Aplastic Anemia, Sickle cell anaemia, and others
  • Congenital neutropenia 
  • Damaged caused to bone marrow due to cancer treatment such as chemotherapy and/or radiation therapy

How can Lyfboat assist you getting Bone Marrow Transplantation in Apollo?

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Lyfboat is a free advisory platform; we do not charge any fees from patients. In fact, we negotiate the price that Indian hospitals offer. In some cases we are able to reduce the cost by negotiating upto 20% of what Hospitals generally offer. We advise the best treatment from the top hospital/surgeon at best price.

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Types of a bone marrow transplant

Autologous Bone Marrow Transplant

‘Auto’ means self, which means that in this procedure, stem cells used in the transplant are taken from the patient’s own body before starting chemotherapy or radiation treatment. The stem cells are harvested and then kept frozen for preservation.

After the treatment with chemotherapy and/or radiation treatments are completed, the stem cells are thawed and transferred back into the patient’s body. These healthy cells help restore the function of blood-forming cells and help to rebuild the immune system as well as maintain a normal amount of blood cells.

Allogeneic Bone Marrow Transplant

‘Allo’ means other, and the stem cells that are used in this type of transplant are collected from another person, called a donor. It is a prerequisite that the genetic compatibility test for donor and recipient genes result is partly or full match.

A special test, known as the HLA test, is performed to screen the donor and determine if they are a good match. Human leukocyte antigen (HLA) is a genetic marker present on most cells in a body, and it is matched in this test.

This determines if the transplant would be successful without complications such as Graft versus Host Disease (GVHD) or organ rejection. A sibling is usually the most likely best match for a person. However, parents, children, and other relatives may also turn out to be good matches. A matching donor, who is not a relative but are still good matches, can also be found in the national bone marrow registries.

To read more about the HLA test, click here.  

When the procedure is done using bone marrow cells from a healthy identical twin of the patient, it is known as Syngeneic Bone Marrow Transplantation. Whereas, the parents or children of the patient can be half matches, and may donate bone marrow. This process is known as Haploidentical Bone Marrow Transplantation 

Umbilical Cord Blood Transplant

It is a type of allogeneic transplant, in which the stem cells used in the procedure are obtained from the umbilical cord, retrieved, and stored after the birth of a newborn baby. The umbilical cord is a rich source of stem cells. It is frozen and stored in a stem cell bank and can be used when required for a transplant. As umbilical cord blood cells are not matured, there is a lesser need of finding a good match. But due to the smaller range of the stem cells, it takes longer for blood count to recover.

Eligibility tests for Blood and Bone Marrow Transplant 

Before starting the treatment, the transplant team will conduct a series of tests and medical evaluations to determine the patient’s eligibility for receiving any type of transplant.

Only after the approval of the transplant team for this procedure, the patient will begin pre-transplant process. The aim of this assessment is to ensure that the patient is at no risk from the treatment and transplant is the best care and treatment based on the diagnosis and overall health condition.

The tests include:

  • Blood tests (cell count)
  • Urine sample for evaluation of kidney function
  • EKG (electrocardiogram) for evaluation of cardiac functions
  • Chest x-ray
  • CT scans of the chest, sinus, abdomen and pelvis, based on particular requirements
  • Bone marrow diagnostic test, if required
  • MUGA scan for heart function
  • Pulmonary function test to evaluate lung functions
  • Psychological consultation, if recommended

After these tests, the doctors will determine which type of transplant would be best for the treatment of patient’s condition. This may also depend on the availability of a donor. There would be tests for donor as well, to determine their suitability for donation and genetic matching.

Bone marrow transplant procedure

The procedure for BMT (ant type) involves three basic steps:

  • Collection of healthy cells from the stem (from patient or donor)
  • Conditioning before the transplant
  • Transfer of new healthy stem cells into the patient’s body.

The procedure is carried out in a hospital or well-established facility and by a trained BMT specialist.

Collection of the Stem Cells: The healthy stem cells can be harvested from 3 sources – peripheral blood (after certain treatment), bone marrow, or umbilical cord. 

Stem cells from the blood are the most common choice for healthy cells nowadays. The patient or donor will be given special medications to increase the number of stem cells in the blood. When this number is achieved, leukapheresis, a very simple procedure will be done to collect stem cells. The blood will be taken from one arm through a thin tube and it will be passed into a machine which will filter out the stem cells, while the remainder of the blood flows out of the machine and back into the body through the arm.

It is a painless process and takes approximately 2 to 3 hours. There will be no need to stay in the hospital overnight. The stem cells will be frozen and preserved in case of autologous transplant. When bone marrow cells are taken from a donor, there would be no need to freeze the cells as they will be transferred into the patient as soon as possible.

Another method is isolating stem cells directly from the bone marrow. The doctor will use a needle to extract bone marrow cells from particular parts of the hipbone. This takes 1 to 2 hours, and the donor is given anesthesia to put them to sleep during the procedure. 

Conditioning

Prior to receiving the new cells, the patient will undergo high-dose chemotherapy or radiation therapy, based on the type of transplant, medical condition, and overall health of the patient. This conditioning process is done to remove the damaged or diseased bone marrow and make space for the new stem cells. It also helps in suppressing the immune system, so that the chances of the body rejecting the new cells are reduced. For cancer patients, it may be part of their treatment plan. The entire process takes almost a week, based on the treatment procedure. However, it can be done on an outpatient basis (the patient won’t need to stay in the hospital overnight). 

Transplant

After conditioning, the patient will be prepared for the transplant. The healthy stem cells are transferred into the patient’s body through a thin tube, called a central line. This might take a few hours. It is a painless process and the patient remains awake for the whole duration.

The new healthy stem cells will migrate through the blood and reach into the bone marrow. They will start producing bone marrow cells and various types of blood cells over time. It might take a few weeks for the blood cell counts to rise and get to the normal level.

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Risks and complications of BMT

After the bone marrow transplant, the patient is at risk of developing the following complications:

  • Infections
  • Breathlessness 
  • Nausea and vomiting
  • Body pains and soreness
  • Fever and chills
  • Lower blood pressure
  • Inflammation in the mouth, throat, and stomach

Long-term side effects may include:

  • Cataract  (clouding of the lens of the eye, causing vision problems) 
  • Damage to the vital body organs
  • Premature menopause 
  • More prone to infections
  • Anemia

The frozen stem cells are stored in a preservative that may cause some side effects. If the patient receives frozen stem cells, they will be prescribed medication to help manage these effects. They may also receive more fluids to help flush out the preservative out from the body.

The factors that may determine the chances of experiencing post- bone marrow transplant complications by a person are:

  • Patient’s age 
  • Patient’s overall health and medical condition 
  • The type and severity of disease being treated
  • Type of the bone marrow transplant performed

Most of these symptoms are temporary and disappear over time. However, there is a risk of some extreme and serious complications after a bone marrow transplant, including:

  • Graft-versus-host disease (GVHD): It may occur when the donor cells start to attack the patient’s body. 
  • Graft failure: The transplanted stem cells fail to produce a new or adequate number of bone marrow and blood cells as expected.
Questions? Let us know.
Vanshika Rawat

Written By Vanshika Rawat

Vanshika Rawat is an experienced content developer. She is very knowledgeable in the field of science and healthcare and has worked under brilliant scientists during her higher education. Vanshika obtained her degrees in Masters in Science and Bachelors in Science (Microbiology with Hons.) from renowned institutions - Panjab University and University of Delhi.
Dr. Surbhi Suden

Verified By Dr. Surbhi Suden

Dr. Surbhi Suden is one of the founders of Lyfboat and a doctor with a renowned name in the Medical tourism industry. She has been working with international patients since 2008 and is a deeply committed professional with a long term vision of transforming the current healthcare scenarios.

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Vanshika Rawat

Written By Vanshika Rawat

Vanshika Rawat is an experienced content developer. She is very knowledgeable in the field of science and healthcare and has worked under brilliant scientists during her higher education. Vanshika obtained her degrees in Masters in Science and Bachelors in Science (Microbiology with Hons.) from renowned institutions - Panjab University and University of Delhi.
Dr. Surbhi Suden

Verified By Dr. Surbhi Suden

Dr. Surbhi Suden is one of the founders of Lyfboat and a doctor with a renowned name in the Medical tourism industry. She has been working with international patients since 2008 and is a deeply committed professional with a long term vision of transforming the current healthcare scenarios.
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