The Success Rate of Bone Marrow Transplants in India

The Success Rate of Bone Marrow transplants in India is around 60 to 85%, patients who underwent an allogeneic transplant for a non-malignant condition had a success rate of 70 to 90% with a related match and 36 to 65% with an unrelated donor

Success-rate-of-BMT-in-India

What is a bone marrow transplant?

A bone marrow transplant can be a taxing experience, yet it is a procedure that can bring a shattered life back on track. 

As the name suggests, a bone marrow transplant replaces the old, defective, or diseased bone marrow with a healthier set of stem cells. The source of these cells can be the patient’s own body or someone related who is a good match. A bone marrow transplant is used to treat a variety of cancers, including leukemia, myeloma, lymphoma, and a few blood & immune system diseases.

Easier said than done, the results of bone marrow transplantation depend on many factors. To make the procedure a success, a patient would need the guidance of an experienced hematooncologist. Furthermore, the choice of the hospital also makes a huge impact on the survival rate and life expectancy post-transplant. 

Many countries offer expertise and a high success rate for BMT. However, the bone marrow transplant success rate in India remains unmatched to date. Let’s dig a little deeper to understand why. 

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Types of Bone marrow transplants in India

 

Autologous BMT

Allogenic BMT

Donor

Patient’s own stem cells unless the bone marrow is compromised

Related or unrelated donor who is either a full-match or a half-match. Ideal order of donor is sibling>MUD>Haplo-donor

Source of Cells

PBSC (Peripheral blood stem cells)

Bone marrow harvest, in some cases PBSC

Risk of GVHD (Graft-vs-host-disease)

Less

High

Immunosuppression

Not required

Required

Time for engraftment

7-10 Days

2 to 4 Weeks

Maximum age limit for the candidates

60 – 70 Years

40 – 55 Years

Malignant Disorders

·       Multiple myeloma

·       Non-hodgkin lymphoma

·       Hodgkin disease

·       Acute myeloid leukemia

·       Neuroblastoma

·       Ovarian cancer

·       Germ-cell tumor

·      Acute lymphocytic leukemia

·      Chronic myeloid leukemia

·       Myelodysplastic syndromes

·       Myloproliferative neoplasms

·       Multiple myeloma

·       Non-hodgkin lymphoma

·       Hodgkin disease

·       Acute myeloid leukemia

Non-malignant disorders

·       Auto-immune diseases

·       Amyloidosis

·       Aplastic Anemia

·       Sickle cell disease

·       SCID

·       Thalassemia etc.

How can Lyfboat assist you getting Bone Marrow Transplant in India?

World's Most Trusted Medical Advisory & Discount Platform

Lyfboat is a free advisory platform; we do not charge any fees from patients. In fact, we negotiate the price that Indian hospitals offer. In some cases we are able to reduce the cost by negotiating upto 20% of what Hospitals generally offer. We advise the best treatment from the top hospital/surgeon at best price.

Why choose India to undergo a Bone marrow transplant?

  • India has witnessed many advancements in the field of medicine, research, and healthcare technology. Over the last few years, the country has come up with new and innovative treatment approaches like CAR-T cell therapy, successful BMT using half-matched donors, T-cell depletion with memory cell infusion, and a better infection profile with strong antibiotics. 
  • India boats an exceptionally high number of JCI-accredited bone marrow transplant centers. These hospitals are equipped with state-of-the-art infrastructure, modern technology, and the latest medical facilities. Bone marrow transplant should be performed in extremely clean surroundings so that the chances of infection are negligible. Almost all bone marrow transplant hospitals in India have HEPA filter rooms, modular operation theatres, and high-tech labs, leaving no scope of negligence during the procedure. 
  • The country also has a pool of skilled and experienced hematologists and oncologists that work together to provide effective treatment and care to all their patients. Doctors and surgeons in India are trained in some of the best institutions and forums in India as well as abroad.
  • Combining years of knowledge with an analytical bend of mind, they are constantly working towards new treatment strategies in cancer and diseases related to the bone marrow. For instance, patients undergoing an allogeneic transplant no longer need to have a bone marrow harvest. Instead, doctors in India are now performing allogeneic BMT with the help of the peripheral blood stem cell (PBSC) method. 
  • Proving its merit and excellence in the field of bone marrow transplant procedures, India has presented a staggering average success rate of 60 to 85%. With a dedicated team of doctors, trustworthy hospitals, and cost-effective treatment, India has become the best place to undergo a bone marrow transplant. 
  • Last but the most important factor that attracts patients to opt for BMT in India is the availability of quality treatment at a fraction of what countries like the US, the UK, Europe, or Thailand offer. The cost of bone marrow transplant in India is:
ProcedureAverage Evaluation CostAverage Treatment Cost
Autologous BMT1300 – 1500 USD15000 – 24500 USD
Allogenic BMT1300 – 1500 USD25000 – 37500 USD
Haplo-BMT1300 – 1500 USD36000 – 50000 USD
Unrelated BMT1300 – 1500 USD65000 – 90000 USD

Life expectancy after bone marrow transplant in India

  • Life expectancy after undergoing a bone marrow transplant in India has increased significantly. This increase in the success rate can be attributed to accuracy in genetic matching, following a strong antibiotic regimen post-transplant, and overall improvement in post-op care. 
  • A bone marrow transplant replaces the diseased bone marrow with a group of healthy and functional stem cells. However, the success of the procedure is different for every condition and every patient. 
  • Statistically speaking, patients who underwent an allogeneic transplant for a non-malignant condition had a success rate of 70 to 90% with a related match and 36 to 65% with an unrelated donor. 
  • Whereas autologous bone marrow transplant has showcased a high success rate for conditions like Ewing sarcoma, Wilms tumor, germ cell tumor, and neuroblastoma. However, there is no significant change in the BMT survival rate for conditions like pediatric malignant cancers. 
  • Understandably, patients in remission or with stable disease have shown better survival rates after a BMT than those who were in advanced stages or in relapse. 
  • Age also plays a huge factor in the survival rate after a bone marrow transplant. A young patient is more likely to survive the disease after BMT than those who are older than 60. 
  • Lastly, post-transplant care and lifestyle also dictate the outcome of the procedure. Compliance with the post-op guidelines and suggestions by the doctor can help a patient to get a second chance at life! 
Simran Bahia

Written By Simran Bahia

Simran Bahia is an experienced content writer with extensive research experience in Immunology and Reproductive Biology. Simran received her Bachelors in Life Sciences from Delhi University, followed by a Master's in Immunology from the Amity Institute of Virology and Immunology. Combining her love for science and writing, Simran enjoys putting a spin on standard methods of medical writing.
Dr. Surbhi Suden

Verified By Dr. Surbhi Suden

Dr. Surbhi Suden is one of the founders of Lyfboat and a doctor with a renowned name in the Medical tourism industry. She has been working with international patients since 2008 and is a deeply committed professional with a long term vision of transforming the current healthcare scenarios.

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Simran Bahia

Written By Simran Bahia

Simran Bahia is an experienced content writer with extensive research experience in Immunology and Reproductive Biology. Simran received her Bachelors in Life Sciences from Delhi University, followed by a Master's in Immunology from the Amity Institute of Virology and Immunology. Combining her love for science and writing, Simran enjoys putting a spin on standard methods of medical writing.
Dr. Surbhi Suden

Verified By Dr. Surbhi Suden

Dr. Surbhi Suden is one of the founders of Lyfboat and a doctor with a renowned name in the Medical tourism industry. She has been working with international patients since 2008 and is a deeply committed professional with a long term vision of transforming the current healthcare scenarios.
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