“The Multiple Sclerosis treatment cost in India for Autologous Hematopoietic Stem cell transplant is USD 20,000 (INR 14,85,000) – USD 25,000 (INR 18,56,000). The cost for treatment with medication and drug therapy varies depending on the dosage required for managing symptoms and the disease course. Other factors which affect the cost include duration of hospital stay, room category, status of the chosen hospital and many others.”
Multiple Sclerosis is an autoimmune disorder which majorly affects the brain, spinal cord, and optic nerves. It is usually characterized by a range of neurological symptoms and gradual disabilities. The disease develop when the body’s own immune system starts to attack the myelin sheath which is the insulating cover that surrounds the nerve fibres.
The neural damage results in disruption of various functions of the nervous system. The damaged tissues is scarred in multiple areas and appear as lesions, and this gives the disease its name – Multiple Sclerosis (MS).
Multiple Sclerosis is the most common autoimmune nervous system disorder and leading cause of disability in children.People within the age group of 20 to 40 are more commonly diagnosed with MS and that’s when the first symptoms usually appears.
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Each patient is affected by Multiple Sclerosis in a different way and it is difficult to predict the course of disease. National Multiple Sclerosis Society and the International Advisory Committee on Clinical Trials of MS in 2013 describes 4 basic types of MS, namely –
The signs of Multiple Sclerosis may vary from person to person, depending on the type and severity of disease and the kinds of neural damage. A range of problems related to vision, movement, speech and swallowing, motor and sensory functions, can occur in Multiple SclerosisMS).
Some of the specific symptoms are –
Depending on the type of Multiple Sclerosis, the symptoms can vary and may come and go in form of attacks or worsen as the disease advances and there may be permanent damage.
While the cause of Multiple Sclerosis is not known yet, it is believed to be linked to genetic predisposition, immune system abnormalities and environmental factors. The risk factors may include:
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Multiple Sclerosis is most commonly diagnosed in people of age groups of 20-30, but it is important to keep in mind that it can develop at any age. There is no single definitive test, as of yet, to determine if a person has Multiple Sclerosis.
A doctor uses various methods to diagnose the disease –
The strategy is to rule out other possible causes for the disorder and check if the symptoms and test results meet the criteria for diagnosing meet Multiple Sclerosis.
Although, there is no complete cure for Multiple sclerosis, certain therapies are available to manage the symptoms in the patient and cope with disability.
The treatment is focused on slowing the disease progression, increasing the remittance period (no neurological episodes) and making the symptoms manageable.
The disease-modifying drugs or therapies are the long-term treatment for MS but cannot cure the disease itself but only aid in slowing the progression and preventing new attacks. For short term treatment – only to relieve symptoms, drugs such as corticosteroid are known to be effective.
The disease modifying drugs prevent symptom flare-ups and delay the advance of the disease. They work by preventing the immune system from attacking the myelin sheath that covers the neurons, which is the effective cause of the disease. These drugs can be given in the form of injection under the skin or muscles or as oral pills. The injectable medication includes:
The side effect of using injectable medications is that they may cause skin irritation at the injection site.
These drugs are taken orally by the patient as per doctor’s prescribed dosage and can help in reducing relapses.
For RRMS in children (10-17) medication, there is only one approved disease-modifying therapy.
The infusion drugs are given directly into the veins by the doctor once in a few months.
The problem with disease-modifying drugs is the adverse effects related to major CNS and cardiovascular system, and prolonged usage may lead to life-threatening diseases. The side-effects of these medications include headache, back-pain, diarrhoea, abnormal liver tests, nausea, high blood pressure and hair loss, among others. Some more adverse effects like liver damage, infertility, acute myeloid leukaemia, etc. have also been noted.
A wide variety of medications are also available to manage the symptoms and vary depending on the kind of symptoms.
Corticosteroids: Most commonly used steroids for MS can be given orally as well as intravenously. These may reduce nerve inflammation and manage the flare-ups. Side effects for these include increased blood pressure, mood swings, insomnia and fluid retention.
Plasma exchange (plasmapheresis): It is used when steroids don’t work. Plasma, the liquid part of blood, is removed and separated from blood cells. The blood cells are sent back into body after mixing with protein solution called albumin. Plasma exchange may be used if your symptoms are new, severe and haven’t responded to steroids.
Physical therapy can help in strengthening and improving the muscle tone. The exercises and stretching with the help of mobility devices can help manage leg weakness and make it easier to perform daily tasks.
Medications for managing symptoms –
Stem cells Transplant for Multiple Sclerosis is a proving to be a promising treatment option with positive results in preventing Multiple Sclerosis progression. Hematopioetic Stem Cell Transplant is one of the treatment approaches for Multiple Sclerosis which aims to improve the disease course and prevent neurological episodes. Multiple Sclerosis is an autoimmune disorder, caused when the white blood cells attack the nerve cells in the body.
The Autologous Hematopoietic Stem Cell Transplant (AHSCT) is a procedure in which patient’s own hematopoietic stem cells (develop into blood cells) are taken out and preserved. These stems cells are at an early stage and can develop into white blood cells that do not harm the myelin sheath. These are then injected back into the patient’s body with objective to reset the immune system. The therapy can lead to improvement in neurological symptoms and medication-free period for the patient with Multiple Sclerosis.
The Multiple Sclerosis treatment cost in India for Autologous Hematopoietic Stem cell transplant is 20,000 – 25,000 USD.
Although symptoms of MS are mostly unpredictable and vary for every patient, they typically include the feeling of numbness and tingling, fatigue, double or blurred vision, imbalance, poor coordination, depression, and trouble with memory and concentration. The symptoms may change over time or disappear/remit completely, or they may persist and worsen as the disease progresses.
With appropriate and timely treatment, most MS patients are able to have a full life with a good life expectancy. A small number of patients may experience the rapidly progressive type of MS, which may result in a more severe health problem at an early stage. Some patients, especially those who are significantly inactive, may experience some typical complications due to a prolonged chronic illness, including infection or pneumonia.
Research studies have shown that individuals with relapsing forms of MS when to begin treatment at an early stage with a disease-modifying therapy and other treatment options, may have a longer life than those who do not take treatment.
No, MS is not directly inherited or contagious. Genetic and certain environmental factors may increase the risk of the disease.
MS does not have a definite cure yet, but the available treatments options aim to alleviate the disease symptoms, improve patients’ quality of life and increase life expectancy.
Amyotrophic lateral sclerosis (ALS) and Multiple sclerosis (MS) are two different types of diseases that have some common features and symptoms.
The key difference between the two is that MS is an autoimmune disease in which the immune system starts attacking the body itself, while ALS is a neural disorder in which the nerve cells in the brain and spinal cord begin to wears away. Both these diseases are treated in a different manner.
The Best Hospitals for Multiple Sclerosis in India are the world-class healthcare facilities with uncompromised dedication towards treating the patients. The hospitals have been accredited by national and international bodies for maintaining impeccable standards of quality and safety. Indian Hospitals are amongst the top destinations for international patients to avail medical treatment from internationally renowned doctors and at an affordable cost.
Gurgaon, India
New Delhi, India
Gurgaon, India
The best multiple sclerosis doctors in India are highly qualified and trained specialists with years of experience. Dr. Rahul Bhargav is one of the best hematologists in India who offers stem cell therapy for the treatment of Multiple Sclerosis.
New Delhi, India
New Delhi, India
New Delhi, India
Gurgaon, India
New Delhi, India
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